ABSTRACT
Chronic myelogenous leukemia (CML) is a malignant clonal disorder of hemopoietic stem cells characterized by abnormal proliferation and accumulation of immature granulocyte. Leukostasis is one of the complications of CML and is characterized by partial or total occlusion of microcirculation by aggregation of leukemic cells and thrombi leading to respiratory, ophthalmic or neurologic symptoms. We experienced a rare case of avascular necrosis of the femoral head as the initial presentation of chronic myelogenous leukemia. A 24-year-old male patient was admitted to our hospital with pain in the right hip joint. The patient was diagnosed to be suffering from chronic myelogenous leukemia by packed marrow with granulocytic and megakaryocytic hyperplasia and the presence of Philadelphia chromosome. The right hip joint pain was attributed to avascular necrosis of the femoral head. And the avascular necrosis could be considered as the complication of chronic myelogenous leukemia due to microcirculatory obstruction of the femoral head. The avascular necrosis of the right femoral head was treated with bipolar hemiarthoplasty.
Subject(s)
Male , Humans , Adult , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis , Femur Head Necrosis/diagnosisABSTRACT
Extramedullary plasmacytoma may originate in any organ, either as a primary tumor or as a facet of systemic multiple myeloma. These solid lesions most commonly affect the upper respiratory tract, gastrointestinal and urogenital tract, skin, and lung. Primary plasmacytoma of the lymph node is a rare hematologic neoplasm, which usually manifests as an enlargement of the cervical lymph nodes with no evidence of any other plasma cell dyscrasia. A 56-year-old man was admitted, due to the presence of multiple palpable masses in the right cervical and submandibular areas. Surgical resection revealed plasmacytoma of the lymph nodes. According to our full work-up, no evidence of the systemic involvement of plasma cell dyscrasia was discovered and thus, the diagnosis of primary plasmacytoma of the lymph node was made. Radiotherapy was administered, and the remnant mass was reduced substantially, to 1 x 2 cm in size. The patient was scheduled to be monitored by a PET CT scan, as well as by a neck CT scan.
Subject(s)
Humans , Male , Middle Aged , Biopsy, Needle , Bone Marrow/pathology , Diagnosis, Differential , Lymph Node Excision , Lymph Nodes/pathology , Neck , Plasmacytoma/diagnosis , Tomography, X-Ray ComputedABSTRACT
Psoas abscess is caused by primary or secondary and most commonly results from direct extension of intraabdominal infections. Staphylococcus aureus is the most common organism for psoas abscess secondary to vertebral osteomyelitis. Tuberculosis, malnutrition, alcoholism, diabetes mellitus, bone marrow failure, and steroid use are responsible for compromise in host defense and consequent increase in the relative risk of psoas abscess. We report here a case of bilateral poas abscess developed in a 58 year old patient with relapsed plasmacytoma in pelvic cavity during chemotherapy.
Subject(s)
Humans , Middle Aged , Abscess , Alcoholism , Bone Marrow , Diabetes Mellitus , Drug Therapy , Intraabdominal Infections , Malnutrition , Multiple Myeloma , Osteomyelitis , Plasmacytoma , Poa , Psoas Abscess , Staphylococcus aureus , TuberculosisABSTRACT
Primary malignant lymphoma of the lung is a very rare disease, which consists of 0.34% of entire malignant lymphoma. The majority are low-grade B-cell tumors, and because of their morphological peculiarities and overall excellent prognosis, many cases, like many other extranodal lymphomas, have been mislabelled as "pseudolymphomas" in the past. For these reasons their true incidence is difficult to estimate. An incidentally discovered mass in the right middle lobe of a 36-year-old woman was operated on November 9, 2001 at Hanyang University Hospital. A right upper lobectomy was done and the pathologic diagnosis of extranodal marginal zone B-cell lymphoma of MALT type was made.
Subject(s)
Adult , Female , Humans , B-Lymphocytes , Diagnosis , Incidence , Lung , Lung Neoplasms , Lymphoma , Lymphoma, B-Cell , Lymphoma, B-Cell, Marginal Zone , Prognosis , Rare DiseasesABSTRACT
Acute respiratory failure with diffuse pulmonary infiltration was occurred in a patient with malignant lymphoma 1month after the 8th CHOP chemotherapy. The ground glass and consolidation appearances on chest C-T in this immunodeficient patient could be presented in many clinical situations such as pneumonia by opportunistic infections(fungal, parasites, viral, and usual bacterial pathogens), anti-tumor drug's pulmonary toxicity and tumor invasion. And the other diseases of acute interstitial pneumonitis, alveolar proteinosis, BOOP, pulmonary edema and alveolar hemorrhage, which could present the same radiological findings, should included in differential diagnosis. This patient was diagnosed as the opportunistic pneumonia by Pneumocystis carinii and probably Cytomegalovirus through bronchoalveolar lavage and transbronchial lung biopsy.